In the ever-evolving realm of fantasy football strategies, the Zero RB approach continues to gain traction, especially for the 2025 season. This strategy involves emphasizing other positions like quarterback, wide receiver, and tight end in the early rounds, allowing managers to secure high-value running backs in the middle to late rounds. As the landscape of running backs changes, identifying the right targets becomes essential.

Round 5 features James Conner of the Arizona Cardinals, who has proven to be a reliable option, consistently performing as a top-12 back while managing significant snap counts. In Round 6, Quinshon Judkins from the Cleveland Browns presents a high-upside opportunity, especially with the departure of Nick Chubb. D'Andre Swift, now with the Chicago Bears, offers solid RB2 potential in Round 7 due to his familiarity with the coaching staff and his consistent usage. Rookies like Kaleb Johnson of the Pittsburgh Steelers and Javonte Williams of the Dallas Cowboys make compelling cases for Rounds 8 and 9, respectively, as they navigate new backfield situations. Rounding out this strategy, Cam Skattebo from the New York Giants, a versatile back, and Tyjae Spears of the Tennessee Titans bring further depth and upside in the later rounds.