Dylan Sampson of Cleveland is Week 2’s bold RB call, after a Week 1 that saw him dominate the Browns’ backfield with 20 touches and 93 total yards. The Ravens bid to bottle the run, but Sampson’s 17.6% target share and 63% backfield role make him a plug-and-play option in most lineups.

Kenneth Walker III and Kyren Williams are primed for bounce-backs. Walker faces a Steelers run defense that yielded to premier backs last week, while Williams should be heavily involved in Seattle’s and Los Angeles’ game scripts. Braelon Allen and Quinshon Judkins add depth, but Judkins isn’t expected back this week, limiting upside.

Ashton Jeanty’s Week 1 usage wasn’t efficient, and the Raiders draw a Chargers defense that can neutralize rookie runners. Jonathan Taylor faces Denver’s stout front, and Bucky Irving’s volume could be offset by Houston’s run defense. The week’s warning signs include rough matchups against strong front-fours and teams with clear run-stopping upside.