Two 3-0 teams collide as Philadelphia visits Tampa Bay in a showdown with major fantasy impact. Hurts’ rushing upside keeps QB1 ceilings high, while A.J. Brown looks to exploit a corner matchup with Jamel Dean. Up front, Vita Vea tests Cam Jurgens and the interior, potentially tugging the game toward the ground. Barkley aims to break a recent drought against a run-stopping Buccaneers front, and DeJean/Shepard duel could swing mid-slot targets. Red-zone efficiency and edge pressure will tilt a tight, must-watch bout.

Expect a grind with a few splash plays that swing DFS lineups and daily bets. Philly seeks a 4-0 start by protecting Hurts and leaning on the run game when the blitz arrives; Tampa Bay eyes a 4-0 start of their own by leveraging interior disruption and Mayfield’s short-to-intermediate game to counter a stout Eagles defense.

The Buccaneers lose Cody Mauch for the year to a knee injury in Week 2 versus Atlanta, and Luke Goedeke exits the same game, leaving an already thin offensive line to absorb a massive hit. A revamped five (Graham Barton, Elijah Klein, Ben Bredeson, Michael Jordan, Charlie Heck) must hold up in Week 3 against a Jets front that can wreck protections. Tristan Wirfs is approaching a return, but timing remains uncertain, amplifying fantasy angles around Tampa Bay’s line and skill players.