Week 2’s Monday Night Football matchup between the Tampa Bay Buccaneers and Houston Texans sets up a slate of start/sit decisions with real fantasy implications. C.J. Stroud is a sneaky QB2 option against a TB defense that has shown air-yard upside, while Nico Collins is positioned for a bounce-back game as Stroud’s likely top target. On the Buccaneers side, Baker Mayfield potently kicked off the year, but Mike Evans draws a challenging shadow in Derek Stingley Jr. Emeka Egbuka has emerged as a rookie-to-roster play, and Rachaad White’s role remains nuanced. Add in streaming kickers and a handful of versatile depth options, and this game could swing several lineups in Week 2.

Focus points include whether Mayfield maintains efficiency against a Houston unit that can generate pressure, if Collins can capitalize on a favorable matchup, and which RBs—White or the clear-cut workhorse in Tampa—will carve out fantasy value. The night’s weathered edges lie in execution around the goal line and how the Texans exploit Tampa Bay’s secondary, while the Buccaneers lean on a high-powered offense to sustain scoring opportunities. Bold moves should be balanced with guardrails on Evans and Schultz to avoid overexposure in tougher matchups.

Kickers Ka’imi Fairbairn and Chase McLaughlin step into potential streaming roles, while tight end Dalton Schultz remains a low-ceiling option. The MNF doubleheader magnifies the upside and risk across lineups, so sharp managers will chase week-long narratives—rookie bursts, matchup-driven ceilings, and the predictable volatility of a Week 2 primetime stage.