Week 21 MLB two-start streaming targets showdown across 34 pitchers scheduled for two starts Aug 18–24, with a clear distinction between under-50% rostered sleepers and popular, rostered bets. Spencer Arrighetti leads theBest Available streamer group for his Houston slate, while Matthew Liberatore offers a steadier floor for WHIP and ERA thanks to favorable Miami and Tampa Bay matchups. The risk tier features Jack Leiter, Jameson Taillon, Dustin May, and Nestor Cortés, each with contrasting risk/reward dynamics against KC, LAA, SF/LAD, and SD/LAD. Post-deadline aftershocks tighten the streaming pool, making pace and pitch mix critiques essential for savvy fantasy managers.

Key names to monitor include Arrighetti, Liberatore, Leiter, Taillon, May, Cortés, and Taillon’s health return, alongside the Padres’ Cortés’ two-start set. The column emphasizes arsenal depth, matchup-driven rostering, and weekly waiver-wire discipline as the landscape shifts after the trade deadline. In weekly waiver-wire terms, these are the kinds of plays that can stabilize ratios while still contributing strikeouts and win potential.