Three home-run props stand out on Monday’s MLB slate: Riley Greene, Shohei Ohtani, and Kyle Manzardo. Greene hits the Houston Astros’ Spencer Arrighetti, a pitcher with a 6.38 ERA this year, amid Greene’s power against right-handed pitching. Ohtani takes on Kyle Freeland of Colorado, who has labored at 5.18 and has given up 16 homers in 22 starts; Ohtani has crushed Freeland in limited history and thrives vs lefties this season. Manzardo faces Zac Gallen of Arizona, who’s allowed a lot of homers this year, while Manzardo has been heating up with 21 HR and strong splits against right-handers. The trio offers plus odds with legitimate paths to a homer, anchored by favorable opponent histories and park factors. For bettors, tonight’s value rests with Greene’s +425 and Ohtani’s +160, with Manzardo at roughly +380 offering a solid ceiling from a late-season Guardians surge.

These picks hinge on matchup leverage and hot-streak momentum. Greene’s historical success against Arrighetti gives him the standout “why not” prop, while Ohtani’s recent diligence against left-handed arms and Freeland’s struggles create a compelling upside scenario. Manzardo’s swing and Gallen’s homer-friendly tendencies set the stage for a late-season clubhouse spark. Taken together, the night looks ripe for a few long-shot dingers and a potential early-week payday.

Ronald Acuña Jr. returns to the Atlanta lineup, sticking in the third slot as the Braves welcome a Guardians visit. Sean Murphy comes back as well, batting seventh, while Drake Baldwin sits and Marcell Ozuna anchors the DH duties. Cleveland counters with a varied, leadoff-heavy mix: Steven Kwan leads off, Jose Ramirez sits in the prime third spot, and Kyle Manzardo, Daniel Schneemann, CJ Kayfus, Gabriel Arias, and Carlos Santana fill the middle of the order with notable xwOBA signals. The Guardians’ volatility mirrors a league-wide pattern of shifting lineups, while Atlanta’s dynamic through Acuña and company remains the central fantasy driver.

For fantasy managers, Acuña’s health and lineup position keep him near the top of the asset list, with power-speed upside in a top-tier slot. Ozuna’s DH assignment could cap his plate appearances but preserves upside in run production. Murphy’s return to catching duties reenters his fantasy calculus, especially in two-catcher builds or daily formats that prize lineup stabilization. Against a Guardians squad that has rotated through 109 lineups in 120 games, the Braves’ star power edges this matchup, while Cleveland’s leadoff edge with Kwan and Ramirez creates a dual-threat dynamic in DFS and daily fantasy markets.

José Ramírez fueled Cleveland’s 4-3 win over Miami with a night that reinforced his status as an elite power presence. He opened and closed the long-ball parade, shredding the Marlins with a multi-homer performance that gave the Guardians the lead in the eighth inning and crown him with franchise-leading multi-HR games (27). Kyle Manzardo joined the party early with a solo shot, while Brayan Rocchio and Gabriel Arias added key RBIs to back Logan Allen’s 5-inning, solid start. Steven Kwan highlighted the defense with a precision outfield assist on a rundown that preserved a crucial lead, and Bo Naylor helped finish it behind the plate. Cade Smith closed out the final outs for the win as Cleveland climbed to 62-56.

The win underscores Cleveland’s depth and Ramirez’s sustained power upside, an obvious boon for fantasy managers hunting long-term pop. Beyond Ramirez, the night showcased a rising cohort—Manzardo’s early homer, Rocchio’s RBI, Arias’ run-scoring hit, and Kwan’s steady glove—that adds multiple viable sources of fantasy value as the Guardians navigate a crowded schedule. Miami’s lineup turnover limited opportunities, but the Guardians’ bullpen mix, with Vogt steering the sequence, suggested 5-6 inning stability plus late-game upside when Ramirez is locked in.