Denver’s IR slate shortens to six after Kristian Williams’ injury settlement, freeing him to join another club. Malcolm Roach and Drew Sanders land on short-term IR, with Week 5 return eligibility if healthy; four others remain on season-ending IR. The Broncos head to Indianapolis as slight Week 2 favorites, navigating roster churn while hoping Roach/Sanders backfill depth later this season.

Two IR moves (Williams off IR, Burton/Gargiulo/Walker/Henningsen still out) compress roster flexibility but could unlock reserve opportunities. Week 1 win over Titans provides a positive note as the team readies for a Colts matchup that could shape early-season defensive identity and fantasy plays.

Roach's calf strain sidelines him for at least four games, forcing Denver to lean on Jordan Jackson and Eyioma Uwazurike for early-season interior disruption. The Broncos promoted Sam Ehlinger to the 53-man roster as an emergency No. 3 quarterback, ensuring depth on game days without counting toward the active roster. Adam Prentice and Levelle Bailey were elevated from the practice squad to bolster fullback and linebacker depth ahead of Week 1 against Tennessee, while SF's injury to Dre Greenlaw looms as a defensive angle for fantasy managers.

Denver's early-season path leans on improved DL rotation, with Roach out and Jackson/Uwazurike stepping up. Ehlinger’s return adds a mobile quarterback option in emergency scenarios, and Prentice Bailey provides insurance at crucial HB/LB spots. Week 1 becomes a test of depth, roster construction, and adaptive game plans as the Broncos navigate Roach's absence and SF's defensive matchup.

The Titans and Broncos open Week 1 with a tight injury picture. L’Jarius Sneed is limited with a knee and listed as questionable; rookie Kevin Winston Jr. is doubtful with a hamstring; Kalel Mullings is also listed as questionable with an ankle for Tennessee. Denver counters with Nate Adkins out (ankle) and Dre Greenlaw (quad) as doubtful while Malcolm Roach (calf) is questionable.

Fantasy players should monitor Sunday’s inactives. Sneed’s status could shift Titans’ coverage and keep Broncos pass catchers in play; Winston Jr.’s absence may test Tennessee’s safety depth; Adkins out tightens Broncos’ TE options, while Greenlaw and Roach doubts could alter interior pressure and run defense.

Bottom line: update-driven decisions will matter. If Sneed is limited or out, expect Denver’s weapons to see more favorable looks; if he’s active, Tennessee’s secondary could hold the line and keep the game more balanced in Mile High.

Denver heads into the opener with key front-seven absences. Dre Greenlaw is ruled out with a quad issue, and Malcolm Roach is sidelined by a Grade 2 calf strain that could cost several weeks. Denver is leaning on Justin Strnad to anchor the middle, with Karene Reid and Levelle Bailey factoring into the rotation as the team contemplates elevating Bailey from the practice squad. Expect Eyioma Uwazurike and Jordan Jackson to shoulder more interior duties as the Broncos adjust on the fly.

With Roach potentially missing extended time, the run defense and interior pressures will hinge on Uwazurike’s burst and Jackson’s ability to hold the point. Nate Adkins is out, and Dondrea Tillman was limited, so the depth chart tightens and fantasy managers in IDP leagues will want to monitor snap shares closely as Week 1 unfolds.

Denver keeps seven defensive linemen on the 53-man roster, a trench-forward move led by Eyioma Uwazurike and Jordan Jackson. They join Zach Allen, John Franklin-Myers, D.J. Jones, Malcolm Roach, and rookie Sai'vion Jones to form a deep interior DL unit. The stance signals a emphasis on run defense and interior pressure; Week 1 against Tennessee will be the first real test and could boost IDP value for multiple Bronco linemen.

The decision frames Paton’s trench-first philosophy, suggesting more consistent snaps for the interior group and potential fantasy upside if the rotation remains disruptive up the middle.