Houston Astros outfielder Jacob Melton is set to miss significant time due to a right ankle injury that has put him on the 10-day injured list, with a potential return not expected until at least mid-July. General manager Dana Brown announced that Melton, who made his big league debut on June 1 and was showing promise with two hits, including a two-run triple in his last game against the Twins, faced a setback after spraining his ankle during play. Brown expressed disappointment, indicating they were counting on Melton as a left-handed bat to bolster their lineup.

Furthermore, the Astros are also being cautious with third baseman Isaac Paredes, who is dealing with a left hamstring strain. Paredes has missed the last three games but may be available for the upcoming series against the Athletics, according to manager Joe Espada. With Melton sidelined, the Astros will need to adjust their roster and strategy, as they had hoped to leverage his early success.