The Chicago White Sox faced a tough challenge in Houston against the Astros, coming close but ultimately falling 4-3. Mike Tauchman ignited hope with a ninth-inning home run, reducing the deficit to one run. The Sox battled throughout the game, with Edgar Quero driving in two runs and Miguel Vargas doubling off the wall as they threatened a comeback. However, Astros closer Josh Hader struck out Austin Slater to seal the victory, marking yet another series loss for the Sox against Houston.

Despite the loss, manager Will Venable praised his team's effort, signaling a growing frustration over losing close games. Sox starter Davis Martin expressed the need for better momentum management, particularly after giving up runs immediately following their scoring efforts. The performance showcased both the potential of the Sox’s offense and the challenges they face in closing out games against elite pitchers like Framber Valdez, who managed to keep the Sox at bay despite their eight-hit performance against him.