The Houston Astros head into PNC Park on June 4, 2025, looking to extend their winning streak against the struggling Pittsburgh Pirates. Houston, currently holding a 33-27 record, recently triumphed over the Pirates with a 3-0 victory in Game 1 of their series. Their momentum reflects a strong stretch, having won 7 of their last 9 games, while the Pirates have faltered, losing 3 of 4.

Tonight's matchup features Ryan Gusto taking the mound for the Astros, who brings a 3-2 record with a 4.62 ERA. Gusto's last outing was shaky, allowing 2 earned runs in just 3.2 innings. Facing him is Pittsburgh's Mike Burrows, still looking for his first win after a rough start to the season, posting an 0-1 record and an alarming 8.64 ERA after allowing 4 earned runs in his last appearance. As the teams clash, MLB betting odds favor the Astros at -140 on the moneyline with a total set at 9.0 runs.