Week 2 leans dog-heavy with four outright underdogs in the Locks of the Week and three more likely to win outright. Caleb Williams and the Chicago Bears face a Lions squad eager to rebound, while Washington's short week against Green Bay tests an offense that flashed in 2024. Jordan Love carries turnover-rate concerns into a high-profile date with Philadelphia, and Drake Maye leads New England into Miami in a get-right spot for the Patriots. The Buccaneers visit Texans as another midpack dog with upside; the slate pivots on quarterback cleanliness and line play.

Value hinges on a few swing factors: Williams' accuracy and decision-making, Love's ability to limit risky throws, and Maye's first true road test. Turnover-worthy throws and pressure rates loom large, while injuries and depth chart shifts shape the underdog cases. These picks demand a mix of contrarian courage and meticulous matchup reading for Week 2 profitability.