Week 5 brings a cavernous DST streaming landscape as byes thin rosters. The Cleveland Browns anchor the top list with a favorable London clash against Minnesota, while the Indianapolis Colts, New York Giants, Dallas Cowboys and Miami Dolphins offer steady floors in strong matchups. Deep-league options like the New Orleans Saints, Carolina Panthers and New York Jets provide upside when offenses stumble. Prioritize sacks, turnovers and game-script over name value.

Savvy managers target mid-tier defenses that thrive in favorable game-plans, and leverage matchup-driven starts to maximize points when rosters are stretched. The emphasis is on exploiting weak offensive lines, vulnerable quarterbacks and high-variance offenses to turn defensive stops into fantasy wins.

Jonathan Taylor is the Week 4 centerpiece for the Colts, carrying a heavy workload and producing elite fantasy upside against the Rams. Daniel Jones has clicked with Indy’s offense, offering dual-threat value that can lift lineups. Sit Josh Downs and DJ Giddens, while Pittman, Pierce, and Tyler Warren provide steadier paths to points. The Rams pose a meaningful test on both sides, making this a matchup where volume and efficiency will separate rosters.

In this clash, expect Indy to ride Taylor early and often, with Jones contributing through both the air and ground. Downs may be quieter than his receptions total suggests, while Pittman and Pierce loom as the top wideouts. Giddens’ role should stay limited behind Taylor, keeping him out of FLEX consideration unless a blow-up opportunity presents itself.

Colts Week 4 depth chart vs Rams highlights key fantasy angles. Giddens outsnapmed Goodson in Week 3, hinting at a lead-back role if health holds; Pierce in concussion protocol could lift Adetomi Mitchell into more targets, while Tenuta remains a healthy scratch and Jalen Travis backs both tackle spots. On defense, Buckner anchors the line with Gallimore and Adebawore rotating; Moore II out weeks means Blackmon or Hilton logs the nickel role. Tuimoloau has been a healthy scratch in two games, underscoring matchup driven rotations that will shape fantasy outputs this week.

Front seven pressure and secondary tweaks will influence Rams exposure. The rotation at weakside linebacker expanded this week with Ajiake, while the Gallimore-Adebawore pair battles for snaps. With Pierce likely limited, and the backfield committee leaning toward Giddens, sophisticate fantasy managers should pin value on Mitchell, Downs and Mallory for potential midseason upticks against a Rams defense that can be schemed through the Colts depth chart.

Week 3 waiver-watch spotlights high-upside stash candidates across the NFL, led by rookies and depth-chart shuffles that could reshape fantasy value in deeper formats. Woody Marks in Houston surfaces as the clear handcuff to Nick Chubb-adjacent potential, while Jeremy McNichols in Washington could seize a bigger role if Ekeler remains out. Brashard Smith in Kansas City and Jalen Coker in Carolina represent long-shot upside for 12-team and deeper leagues, with Luther Burden III and Ja'Tavion Sanders offering TE/WR flex appeal in Chicago and Carolina. Spencer Rattler in New Orleans stands out as a multi-week QB stash, and DJ Giddens and Kyle Monangai provide late-round RB intrigue behind volatile backfields.

These players are widely available in Yahoo leagues and could become must-starts if depth-chart opportunities align. The article stresses patience and smart rostering, as most of these stashes carry minimal immediate value but offer meaningful season-long upside with the right breaks.