Denver’s heartbreak on the road to Indianapolis came with a brain-fade finish: a 29-28 loss driven by late penalties, missed opportunities and a 60-yard game-winner that capped a sequence of missteps. Dobbins’ delay of game, a wayward punt of momentum, a doinked 42-yarder by Wil Lutz, and a controversial Uwazurike/Tillman call highlighted a night of cognitive disconnects for Denver.

With the Colts stealing momentum late, questions loom about Sean Payton’s clock management and Shane Steichen’s finish drive. For fantasy managers, the ending reshapes expectations around Broncos targets, kickers and defense, and it plants early-week narratives ahead of matchups with the Chargers, Bengals and Eagles.

In all, the ending becomes a cautionary tale for late-season optimism and a reminder that execution in crunch time can redefine a season’s arc and fantasy value alike.

Week 2 flashed a fantasy fireworks show: Jared Goff lit up Chicago for five touchdowns and 300+ yards, Russell Wilson surged to 450 passing yards with three TDs, and Lamar Jackson turned in four passing scores. Drake Maye and Daniel Jones added big rushing and passing days, while Jonathan Taylor and James Cook topped the day at the RB position. Amon-Ra St. Brown shredded the secondary with three TDs and 9 grabs, and Nabers, Wan’Dale Robinson, and Puka Nacua paced the WRs with large yardage and scores. Tight ends delivered in spades, kickers slammed long-range kicks, and defenses topped the box score, making Week 2 a goldmine for fantasy managers.

Beyond the headline performances, the week underscored the value of dual-threat upside, high-volume passing, and even some surprise contributors. It tightened up the learning curve for lineup construction, reinforced the staying power of elite offenses, and kept sleepers in play as rosters pivot toward playoff positioning. For fantasy managers, Week 2 was a reminder: pace and opportunity often drive the best Week-to-Week gains in standard scoring formats.