Rams return to SoFi Stadium to face an unbeaten Colts led by Daniel Jones and Jonathan Taylor, a pairing that has Indy clicking on offense and bolstering a defense that can pressure. LA must monitor Davante Adams’ hamstring and the health of Higbee as Buckner and company try to melt the Rams’ blocking scheme. The matchup doubles as a fantasy crossroads, with Colts’ skill players offering upside if Jones stays efficient and Rams options shaped by injury reports and game flow.

Fantasy notes center on Jones and Taylor as keys for Indy, Adams and Higbee for LA, and the defensive pieces that could swing scoring. Injuries and game script will decide who emerges as a workable weekly play, with waivers and lineup decisions tight as this clash unfolds in a pivotal week.

Rams try to rebound after a dramatic loss to Philadelphia, facing an unbeat en Colts squad boosted by Jones and Taylor. Jones has found a late-career spark, piling three pass TDs and three rushing TDs with no picks, while Taylor anchors a red-hot offense that’s shown balance and efficiency. The Colts also boast a sturdy defense, sitting seventh in total defense, setting up a tougher-than-expected test for L.A. fantasy managers.

Injury notes cloud the Rams’ potential plays: Adams, Havenstein, Higbee, and Parkinson are all listed as questionable but expected to play, while the Colts’ Buckner is questionable and Moore and Goncalves are dealing with injuries. The matchup pits a Rams club hungry for momentum against a Colts squad with a rhythm that could reshape fantasy rostering this week.

With SoFi Stadium on the line and a schedule shift from a near-miss vs the Eagles to a hot Colts attack, this game could hinge on which offense gets moving first. Expect snaps and targets to swing on the health of key skill players, and a defense that may dominate middle-of-field battles as both teams seek to seize control early.