Buffalo Bills host the Miami Dolphins in Thursday Night Football as Week 3 opens, with Buffalo riding a 2-0 start and Miami slumping 0-2. Bills are the heavy -13.5 favorite, and the slate features two undefeateds in Philly vs Los Angeles and Arizona vs San Francisco. Giants vs Chiefs caps Sunday Night, while Lions visit Ravens on Monday Night Football. The full card lists every Week 3 game with lines, totals, and FPI odds to guide fantasy lineups and bold bets.

Fantasy emphasis centers on exploiting high-scoring expectancies and favorable game scripts. Track line moves and totals for starts like top offenses and potential shootouts, while identifying mid-range sleepers in games with clear target volume or pace advantages. Use the odds and projections to balance upside with risk as Week 3 decisions tighten.

Week 2 rewarded fantasy managers with a surge of high-scoring performances, including six players topping 30 PPR points. The big caveat is the sustained absence of Joe Burrow, which reshapes the Cincinnati offense and creates streaming opportunities for Browning, Stafford, Jones, and Mac Jones. Early Week 3 looks favorable for Bengals replacements, Rams passers, and Colts play-callers, while several running backs and wideouts—Tuten, Allgeier, Doubs, Ayomanor, Hopkins—emerge as viable fills. Tight ends Juwan Johnson and Zach Ertz remain steady, and streaming defenses like the Packers, Colts, and Chiefs offer upside depending on Week 3 matchups.