Top wideouts by PFF receiving grade through Week 2 of 2025 showcase a mix of elite playmakers and breakout rookies. Puka Nacua is policing the slot and earning repeated targets, Amon-Ra St. Brown engineered a standout Week 2, while Tetairoa McMillan posted a premier rookie debut and looks like a sustained threat. Garrett Wilson’s Week 1 efficiency and Tyreek Hill’s big-play profile anchor the upper echelon, with Ja'Marr Chase and CeeDee Lamb leading the strong core behind them.

The field also features a mix of proven veterans and emerging talents—Zay Flowers, Jaxon Smith-Njigba, Malik Nabers, and others—whose target shares, yards after catch, and separation grades hint at persistent fantasy upside despite variable game plans. The data underlines the value of slot vs outside targets, press coverage, and open separation in driving fantasy points and weekly ceilings.

Week 3 kickoff features Bills vs. Dolphins as the marquee opener, with two high-powered offenses expected to push the pace and fantasy scores. The 16-game slate centers on division battles, star matchups, and injury news that will shape start/sit calls and DFS lineups throughout the weekend.

Tools and projections from PFF guide the edge battles, run defenses, and pass-blocking duels that fantasy managers chase. Expect tight ends and backfields to factor in strong ways as teams navigate a short week and pivotal early-season tests.

Rams host Eagles in a high-stakes playoff rematch, powered by Stafford’s accuracy and Puka Nacua’s breakout as the offense gains a timely edge. LA’s improved protection keeps the ceiling high and gives fantasy managers a reason to chase a big day from Stafford and his rising target.

From the power-rankings lens, Los Angeles sits as a rising NFC contender, while Philadelphia remains a top-tier test. A Rams win could tilt the NFC narrative and push LA further into the elite, making complementary football on both sides of the ball essential for success.