Six Week 1 WR/CB pairings shape fantasy lineups, with three to target and three to dodge. Emeka Egbuka projects as a WR2 for TB against Atlanta’s weaker corner group, while Tee Higgins draws a high-volume, favorable matchup for Cincinnati against Cleveland’s depleted perimeter corps. Marvin Mims Jr. has big upside for Denver versus a Titans secondary with exploitable coverage. Conversely, DK Metcalf could face shadowed sales against Sauce Gardner, Tutu Atwell against Jalen Pitre, and Wan’Dale Robinson versus Mike Sainristil, making benching prudent in some formats.

Injury and game-script context—Week 1’s high o/u and Denver’s pass-friendly pace, plus New York’s aggressive man schemes—amplify the volatility. The piece highlights how preseason grades, target rates, and YPRR metrics inform start/sit calls and DFS exposure, guiding savvy managers through week one’s thin margins.

Rams Week 1 roster is led by Matthew Stafford with Stetson Bennett IV in the wings, and Kyren Williams carrying the backfield alongside budding receivers Puka Nacua and Tutu Atwell. Higbee anchors the TE spot with a supportive tight end group, while the line protection comes from Steve Avila and Rob Havenstein. Cobie Durant and a versatile secondary headline a defensive backfield, complemented by a lean but capable practice squad to inch into the season with depth.

Depth pieces on the practice squad—AJ Acuri, Wyatt Bowles, Tru Edwards, Cam Lampkin and others—give the Rams flexibility for Week 1 and beyond, allowing Stafford to exploit play-action and quick-hitting throws while Williams, Nacua and Atwell maximize opportunities in a balanced attack.

Adams signs with the Rams, giving Matthew Stafford a veteran outside threat and a high-floor target alongside Puka Nacua. LA aims to raise its scoring and push past last year’s NFC playoff exit with a deeper pass game headlined by Adams, Nacua, Higbee and a crowded TE room, while Kyren Williams anchors the run game.

Stafford’s health and a reshaped offensive line are under scrutiny as LA builds around a 1,000-yard duo potential with Adams and Nacua. The Rams gamble on rookie and mid-round WRs to diversify routes, with McVay orchestrating a more multi-tight-end offense to stretch defenses and boost fantasy output across the board.