The analysis of the 2025 NFL Draft reflects a mixed bag for the San Francisco 49ers and their NFC West rivals. The 49ers showcased a strategic approach, filling critical needs through their 11 picks, which earned them an overall grade of B-minus to A-minus. Notably, the drafting of defensive linemen Alfred Collins and Mikel Williams suggests a focus on strengthening their rush defense.

On the other hand, the Arizona Cardinals made headlines with their bold selections, including Walter Nolan and Will Johnson, who were top prospects mocked to the 49ers. The Seattle Seahawks also made strategic moves, acquiring players like Gray Zabel and the intriguing Nick Emmanwori, further bolstering their defense and special teams. Meanwhile, the Los Angeles Rams opted for depth over star power, trading out of the first round and selecting solid contributors, but raising questions about their long-term strategy. With the division becoming increasingly competitive, the impact of these drafts will unfold as the season progresses.