Luis Castillo and Sean Manaea square off in Player’s Weekend aroma, a marquee MLB matchup with fantasy ripple effects. Castillo’s strikeout upside and control mix against a Mets lineup that’s shuffled by early-season injuries sets floor and ceiling expectations for DFS and season-long holds. The Mariners pivot around Naylor’s late scratch, with Eugenio Suárez and Dominic Canzone moving up and Mitch Garver stepping into DH, reshaping daily lineups for both teams.

Luke Raley returns from injury, while Logan Evans and Miles Mastrobuoni land on the injured list, prompting Tayler Saucedo’s arrival. Seattle’s historical notes—Félix Hernández’s peak performances—underline the franchise’s recent peak-to-plate discipline and power. This game blends a high-strikeout, high-variance start with patchwork lineups that could unlock opportunistic sleepers and riskier stacks in daily fantasy.

Projected game time is 4:10 PM PT on ROOT Sports, with radio coverage on KTTH. In fantasy terms, Castillo’s ace-grade upside versus Manaea’s potential floor makes this a card to target for strikeouts and wins, while the shifting lineup around Naylor and Raley’s return could buoy or suppress value across the Mariners’ table. The Mets’ bullpen and late-inning leverage are critical dominoes in deeper formats.

Week 13 of the MLB season brings a host of outfield waiver wire options for fantasy baseball enthusiasts. Notable picks include Lars Nootbaar and Alec Burleson of the St. Louis Cardinals, both thriving during a seven-game week. Nootbaar showcases a strong hard-hit rate, while Burleson's recent performance includes multiple home runs and a high batting average. Jeff McNeil of the New York Mets and Victor Scott, also from the Cardinals, provide versatility and speed, respectively. In the deeper leagues, keep an eye on Jake Mangum of the Tampa Bay Rays and Luke Raley from the Seattle Mariners, both of whom offer potential upside as they re-enter their teams' lineups.

Assessing the matchups this week, teams like the Braves and Cubs are set for extended play, making their players prime streaming candidates. With six teams scheduled for seven games, maximizing plate appearances is crucial for fantasy success. Players like Matt Wallner of the Minnesota Twins and Harrison Bader present power-speed combinations, essential for fantasy rosters. As the season progresses, monitoring these emerging talents could provide significant boosts to your fantasy squad.

Injuries are a common challenge in the fantasy baseball landscape, and stashing players can yield significant dividends. This week, focus on Tanner Houck, a SP for the Boston Red Sox, who, despite a rough start to 2025, has potential to return to form following an injury stint. Shane Bieber, once a dominant force for the Cleveland Guardians, remains on the wire but is nearing a return, making him a prime candidate for those with IL slots. Meanwhile, Matt Wallner and David Fry are also worth considering. Wallner is expected back soon and offers good OBP metrics, while Fry, eligible at multiple positions, can add depth to your lineup. Lastly, Luke Raley, with his ability to hit against right-handed pitching, presents a unique upside if you can afford to wait.

As the fantasy baseball draft season heats up, targets in the later rounds can make or break a team. Players with multi-position eligibility are especially valuable, providing flexibility to navigate injuries or off days. Look for candidates with an ADP of 175 or lower, offering a mix of batting average, home runs, and stolen bases. Key players like Brendan Donovan of the St. Louis Cardinals and Ceddanne Rafaela from the Boston Red Sox have the potential to contribute across multiple categories while providing roster flexibility.

For those seeking late-round sleepers, Christopher Morel of the Tampa Bay Rays and Luke Raley of the Seattle Mariners are intriguing options. Morel’s power potential coupled with eligibility at multiple positions can help fill gaps, while Raley's career-high plate appearances last season hint at further production. As the season approaches, these players could be the difference between a good fantasy team and a championship contender.