Luis Castillo and Sean Manaea square off in Player’s Weekend aroma, a marquee MLB matchup with fantasy ripple effects. Castillo’s strikeout upside and control mix against a Mets lineup that’s shuffled by early-season injuries sets floor and ceiling expectations for DFS and season-long holds. The Mariners pivot around Naylor’s late scratch, with Eugenio Suárez and Dominic Canzone moving up and Mitch Garver stepping into DH, reshaping daily lineups for both teams.

Luke Raley returns from injury, while Logan Evans and Miles Mastrobuoni land on the injured list, prompting Tayler Saucedo’s arrival. Seattle’s historical notes—Félix Hernández’s peak performances—underline the franchise’s recent peak-to-plate discipline and power. This game blends a high-strikeout, high-variance start with patchwork lineups that could unlock opportunistic sleepers and riskier stacks in daily fantasy.

Projected game time is 4:10 PM PT on ROOT Sports, with radio coverage on KTTH. In fantasy terms, Castillo’s ace-grade upside versus Manaea’s potential floor makes this a card to target for strikeouts and wins, while the shifting lineup around Naylor and Raley’s return could buoy or suppress value across the Mariners’ table. The Mets’ bullpen and late-inning leverage are critical dominoes in deeper formats.