Keon Coleman is an upside play for Buffalo in Week 1, but his groin comes with risk and his role hinges on how the Bills deploy theirWR corps after adding Joshua Palmer. Coleman flashed big-play ability in flashes but lacked consistency, leaving him as a risky WR3 in 12+ team leagues—though a big game against Baltimore could accelerate his breakout arc if he’s healthy.

Palmer’s arrival hints Coleman remains the downfield threat, but Week 1 could skew toward a higher target share for Palmer or the run game. Managers should monitor practice reports closely; Coleman’s Week 1 value may hinge on health, and his ceiling is highest in shootouts.

Overall, Coleman’s Week 1 upside is real but not guaranteed. If groin limits him, Palmer and the Bills’ others will soak up targets, capping Coleman’s floor. Still, in deeper formats, a healthy Coleman could deliver a breakout, especially as the Bills tilt toward a fast, vertical offense this season.

Buffalo Bills bettors have three clear angles this season: Joey Bosa, Keon Coleman, and Josh Allen each loom as solid overs plays in Caesars totals for 2025. Bosa, fresh to a new club, is pegged for 6.0 sacks, Coleman for 1,000+ receiving yards, and Allen for 26.5 TD passes, with injury status on Coleman watched closely. The bets ride on a high-powered Bills offense and healthy seasons from the trio, offering plausible paths to value in a loaded AFC landscape.

These Over bets hinge on durability and usage: Allen remains a TD-driving force, Coleman has upside in Joe Brady’s scheme, and Bosa’s pass rush could recapture a double-digit sack cadence in Buffalo. The board’s odds invite aggressive yet informed wagering, especially if Coleman’s groin issues clear and Bosa’s adaptation to a new environment pays off.

Keon Coleman’s Week 1 status looms after a groin injury landed him on the Bills’ injury report, leaving his availability for Baltimore in doubt. If Coleman sits, Buffalo will lean on Khalil Shakir and Joshua Palmer as primary Week 1 targets, with Tyrell Shavers potentially stepping into a bigger role and Elijah Moore as an additional contingency. The situation keeps a close eye on practice progress through the week, with several depth options ready to deploy.

Elijah Moore is among the veterans who could see expanded opportunities if Coleman is limited or unavailable. The Bills’ depth behind Coleman includes Shakir, Palmer, and Shavers, with Curtis Samuel as a potential deeper option in certain packages. Fantasy managers should monitor the practice report and lineup shifts as the week unfolds ahead of the Ravens clash.

Week 1 sleepers could reshape opening-week rosters. Five names ride favorable matchups and clear volume: Hunter, Ekeler, Legette, Tillman, Coleman. Hunter faces a Panthers unit that coughed up yards in 2024, offering a path to early targets. Ekeler should command touches with backfield uncertainty around his depth chart. Legette and Tillman stand to benefit from target opportunities and a pass-happy Week 1 script, while Coleman can leverage a tough opener for Baltimore’s secondary.

These bets emphasize upside over safe floor, giving fantasy managers a chance to pivot from predictable Week 1 lineups to explosive performances that could seed breakout seasons. The underlying theme is high-leverage opportunities in Week 1 that could yield top-10 weeks for multiple sleepers at their respective positions.