DeWayne Carter's Achilles tear ends his 2025 season before it begins, leaving Buffalo with interior-line depth questions. Carter appeared in 11 games as a rookie in 2024, delivering 14 tackles with 5 for loss and three QB hits. The Bills now face how to fill those snaps as Carter’s absence amplifies questions about their run defense and interior pressure.

Two DTs on the practice squad, Zion Logue and Jordan Phillips, could be elevated to the 53-man roster to stabilize the rotation. Expect Ed Oliver to shoulder more responsibility up the middle, while depth pieces step into situational roles. Fantasy angles center on how quickly Buffalo can sustain interior disruption against efficient inside runs and quick-hit passes.

The Pittsburgh Steelers made a bold choice in the NFL Draft, selecting Oregon defensive tackle Derrick Harmon with the 21st overall pick, despite the availability of quarterbacks Shedeur Sanders and Jaxson Dart. General manager Omar Khan emphasized their confidence in Harmon, describing him as possessing the 'Steeler DNA' necessary to bolster their aging defensive line, which is currently led by veteran Cameron Heyward.

Coach Mike Tomlin expressed excitement about Harmon’s potential to dominate against both the run and the pass. This decision reflects the Steelers' strategic focus, aiming to strengthen their defense while maintaining confidence in their current quarterbacks, indicating a long-term vision for the team's success. Harmon recorded five sacks in his final collegiate season, showcasing his capability to impact games at a high level.

The Buffalo Bills have released rookie defensive tackle Zion Logue, leaving them with 52 players on their roster. This move has sparked speculation about how they might utilize the open spot, with veteran safety Micah Hyde's potential re-signing being a popular topic.

While Hyde's return could provide depth and experience, concerns about his health and performance after a lengthy absence from the game complicate the situation. The Bills must weigh the benefits of bringing back a familiar face against the realities of Hyde's current condition and the performance of their existing players.

The Buffalo Bills face a challenge in their Week 9 game against the Miami Dolphins, as wide receiver Amari Cooper and cornerback Christian Benford will not play due to wrist injuries. Cooper, a recent acquisition from the Cleveland Browns, has made an immediate impact, while Benford has emerged as a critical defensive player this season.

With both players sidelined, the Bills will look to their other receivers and defensive backs to step up. Jalen Virgil has been promoted to fill Cooper's spot, while Kaiir Elam may start in place of Benford. The team hopes to maintain their momentum despite these setbacks.

The Buffalo Bills face a challenging Week 8 matchup against the Seattle Seahawks, missing key players Terrel Bernard and Curtis Samuel. Bernard, the starting middle linebacker, is sidelined due to an ankle injury, adding to his previous absence from two games this season. He has made significant contributions when healthy, recording 32 tackles and one interception.

Curtis Samuel, a wide receiver, will also miss the game after suffering a pectoral injury. His absence opens the door for Jalen Virgil, who will make his debut with the Bills after being elevated from the practice squad. The inactives list also includes safety Mike Edwards and linebacker Edefuan Ulofoshio, among others, as the team adjusts for the upcoming game.