Josh Simmons is out for Kansas City, and Jaylon Moore will start at left tackle with Wanya Morris in reserve. Mahomes has protected with a rotating blind side in five Super Bowls, and Moore’s first start this season adds urgency. Detroit’s secondary is decimated with four corners sidelined, though Kerby Joseph and Brian Branch are active. Taylor Decker is inactive for the Lions, amplifying concerns about pass protection. Inactives: Chiefs – Fulton, Wiley, Mitchell, Herring; Lions – Arnold, Maddox, Decker, Vaki, Cunningham, Wingo, Strickland.

The matchup hinges on Chiefs' approach to slow down Detroit’s depleted secondary and Lions’ ability to pressure Mahomes despite injuries. Fantasy angles point to Chiefs pass-catchers benefiting from quicker reads and possible red-zone opportunities, while Detroit could lean on run-heavy looks and opportunistic defense if the Chiefs protect selectively.

Xavier Worthy is active for Monday night as the Chiefs host the Jaguars after an ankle scare, with Kansas City leaning on him to lift a passing attack that welcomed his return. The Jaguars boast a stingy early-season defense that has produced three takeaways and allowed under 400 yards per game, but they’ll be without Travon Walker on the edge. Kansas City also shuffles its lineup: Omarr Norman-Lott is inactive, Mike Danna is back, and Kristian Fulton is out, underscoring the game’s fantasy implications at wide receiver and pass rush.

With Worthy ready, the Chiefs’ aerial upside rises, even as Jacksonville’s defense remains stout. The absence of Walker could tilt the balance toward the Chiefs’ passing game and open up opportunities for other KC receivers, while the Jaguars’ bottom line—few sacks allowed—puts the onus on Kansas City to win through sustainable drive progress and red-zone efficiency.

Week 2 inactive lists for the Chiefs and Eagles were released ahead of the Arrowhead showdown. Chiefs inactive: Jalen Royals, Xavier Worthy, Jared Wiley, Elijah Mitchell, Hunter Nourzad, Malik Herring. Eagles inactive: Dallas Goedert, Azeez Ojulari, Tanner McKee, Will Shipley, Ogbo Okoronkwo, Drew Kendall.

Inactives are determined for injury status, coaching decisions, or other reasons and must be disclosed about 90 minutes before kickoff. With these absences, fantasy managers should anticipate deeper roles for reserve players and possible line and rotation changes on both sides.

Three plays, 49 yards, and one veteran tight end rose to the top for Kansas City in Week 1 of the NFL preseason. Robert Tonyan hauled in three passes for 49 yards to lead the Chiefs’ tight ends, a notable performance that hints at a real depth chart battle behind Travis Kelce. Jared Wiley joined the mix with a two-yard grab, illustrating the club’s willingness to test its backup options in the wake of a forgettable offensive showing. The coaching staff was left with meaningful decisions as cuts loom and roster spots tighten. Tonyan’s production could tilt the balance toward a secure spot on the 53-man roster, while Wiley’s contribution keeps a young secondary option in play. Kelce remains the focal point, but Tonyan’s outing adds a layer of intrigue in the Chiefs’ pass-game plans and red-zone look. KC’s TE room suddenly feels multi-faceted, which could influence late-round fantasy picks and weekly streaming decisions if the trend continues.