Arizona hosts Carolina in Week 2 with a chance to start 2-0 at State Farm Stadium, a feat not achieved since 2021. Gannon emphasized rapid three-phase improvement after Week 1 and adapting to Blount’s season-ending injury, pushing interchangeable players into elevated roles. Carolina counters with a mobile quarterback, a strong O-line, and Hubbard in support, plus emerging targets like McMillan. Week 2 will test Cardinals’ depth and how quickly the defense can gel behind its corners and pass rush.

Fantasy takeaway: Blount’s absence nudges opportunity across Arizona’s defense and depth chart, while Hubbard remains a focal point for Carolina. McMillan’s Week 1 flashes hint at red-zone and gadget usage, and the Cardinals’ secondary will be tested by Carolina’s balance. This game serves as a proving ground for Gannon’s plan and for players stepping into expanded roles across three phases.

Rhattigan lands on the Steelers active roster for Week 2, stepping in for a defense thin at multiple spots as Malik Harrison goes to IR. With injuries to Porter Jr, Harmon and Elliott, Pittsburgh adds veteran depth while James Pierre returns on game day escalation. The reunion angle adds edge as Rhattigan faces Seattle, his first NFL stop before a long arc through the league.

Week 2 survival pools collide with brutal SF injuries as Purdy, Kittle and Aiyuk sit or are limited, leaving the 49ers vulnerable in New Orleans. SF still sits as a small road favorite, but the model-backed winner is not the favored San Francisco slate. Across the board, Browns, Lions, Bills, Rams, and Panthers offer the most reserve-friendly routes in a week light on obvious chalk. The advanced projection behind SportsLine leans hard toward a non-SF winner in Week 2, a rare call that could redefine typical survivor play.

With Purdy out and SF retooling, the model shifts toward a high-probability, yet less obvious, Week 2 path and urges readers to check its pick for the exact play. New users can claim promo bonuses while studying the model’s 10,000-simulations and continued track record. The takeaway: trust the numbers, not just the eye test, in a Week 2 full of injury-driven pivots.