The Panthers head to Foxborough after a 30-0 win but Week 4 brings a tough injury pill that could reshape fantasy plans. Out are Patrick Jones II, Xavier Legette, Ja'Tavion Sanders and D.J. Wonnum, with Sanders sidelined by an ankle injury likely to linger. Tershawn Wharton is questionable after a hamstring tweak, while Tetairoa McMillan and Chuba Hubbard are limited with calf issues. Others like Rico Dowdle, Jaycee Horn, and Taylor Moton are rested, and Hunter Renfrow is not facing an injury concern.

McMillan leads Carolina with 14 catches for 216 yards through three games, making his availability pivotal. The Panthers promote Jimmy Horn Jr. to the active depth chart, potentially widening the target tree if McMillan misses time. The 1-2 Panthers face the 1-2 Patriots in a 1 p.m. ET kickoff on FOX, looking to exploit depth and maximize opportunities from a reshaped skill-position group.

Ja'Tavion Sanders is out weeks with a high ankle sprain, leaving the Panthers with Mitchell Evans and Tommy Tremble as the immediate TE options. Trade chatter intensifies around David Njoku from Cleveland as Carolina pivots to a premium upgrade to support Bryce Young and the passing game. Cleveland could cash in for 2026 draft capital with Harold Fannin Jr. rising, making Njoku expendable. Carolina eyes a quick path to the NFC South race, leveraging added weaponry beyond Tetairoa McMillan, Xavier Legette, and Hunter Renfrow.

The plan hinges on improving Young's development and the offense's rhythm, especially with a thin TE depth chart and a need for reliable targets. If aNjoku deal materializes, Carolina would gain a high-end safety valve, elevating efficiency and making the pass game more attack-minded as they chase meaningful wins in a competitive division.