Georgia Bulldogs defensive tackle Nazir Stackhouse is projected to be selected as the last pick in the 2025 NFL Draft, with the potential to be labeled as 'Mr. Irrelevant.' This title is often associated with the final selection in the draft, which historically has not yielded many notable careers. However, exceptions exist, such as Brock Purdy, who has thrived despite being chosen last in the 2022 draft.

Stackhouse's prospects may indicate a high likelihood of going undrafted due to a competitive defensive line class. Although his projected pick at number 257 suggests he could be a late-round selection, the depth at his position leaves his draft status uncertain.

The Detroit Lions are elevating Kelvin Sheppard from linebackers coach to defensive coordinator following Aaron Glenn's departure to coach the New York Jets. This marks a rapid progression for Sheppard, who is just in his third season with the Lions and has received mentorship from Glenn himself. Head coach Dan Campbell emphasized the need for continuity and finding the right staff to maintain the team's defensive edge. Sheppard, known for his fiery coaching style, has been with the Lions since 2021 and previously played for several NFL teams, including the Buffalo Bills and Indianapolis Colts.

Dane Jackson is making his debut with the Carolina Panthers after being activated from injured reserve. He had been recovering from a hamstring injury sustained during the summer.

In addition to Jackson, the Panthers have signed defensive tackle T.J. Smith from the practice squad, while releasing cornerback Troy Hill and waiving center Andrew Raym to accommodate these changes. The team also elevated Shaq Lawson and Shaq Quarterman from the practice squad for their upcoming game against the Washington Commanders.