San Francisco’s Week 6 setback vs. Tampa Bay exposed injury-depleted depth and a string of costly mistakes. Fred Warner’s ankle injury crippled the defense’s leadership, and Nick Bosa’s season-ending ACL injury left the pass rush thin. The 49ers’ lack of interceptions extended to 13 straight games, while their only sack came from rookie Mykel Williams. Offensively, Mac Jones threw for 347 yards with two picks and six sacks, yet Kendrick Bourne delivered another big game with 142 yards on five catches. Eddy Pineiro was perfect on four field goals, and SF’s rushing attack stagnated at 67 yards. A late fourth-quarter penalty and two turnovers sealed the loss, but San Francisco still leads the NFC West at 4-2 as other contenders pace the division.

Penned as a game of margin for error, the result highlights how injuries and discipline swing outcomes in close games. SF must lean on Bourne’s versatility and Pineiro’s reliable leg while hoping health returns to the defensive leaders. Until Bosa and Warner return, the meticulous, mistake-free football that carried SF earlier in the year is harder to maintain.

Baker Mayfield sparked a gritty Tampa Bay win over San Francisco, guiding a depleted receiving corps as Evans, Godwin and McMillan were sidelined. Mayfield’s improvisation and critical third‑down scrambles kept the offense rolling and extended drives late in the game.

Kevin Durant chimed in with a NSFW compliment, amplifying Mayfield’s rising profile beyond football after a highlight-worthy third‑quarter run. With Emeka Egbuka injured, the Bucs leaned on depth and Mayfield’s playmaking as fantasy managers weigh Week-to-Week upside in a thinning WR group.

Durant’s Texas‑OU tie adds a cross-sport twist to the moment, while the game itself underscored narrative-rich value for Mayfield and a few breakout Bucs receivers stepping into larger roles in coming weeks.

Two Florida Gators alumni earned NFL Week 5 Player of the Week honors. Eddy Pineiro powered the San Francisco 49ers with four made field goals, including a 59-yard career best, while Chimere Dike of the Tennessee Titans delivered a game-changing 65-yard kick and memorable multi-role production as a rookie.

Dike piled up 136 return yards on four kickoff runs, plus 33 on punt returns and two catches, while Pineiro’s perfect accuracy—11-for-11 on the season—solidified SF’s kicking game after Moody’s struggles. The award marks Dike as the first rookie to claim the honor this season, and Pineiro as a clutch, long-range weapon for the 49ers.

Injuries forced San Francisco into unfamiliar roles, but they beat Los Angeles 26-23 to seize the NFC West lead. Alfred Collins forced and recovered a goal-line fumble, and Kendrick Bourne piled up 142 yards on 10 catches as Mac Jones steered the offense in Purdy's toe-injury absence.

Stafford threw for 389 yards and 3 TDs, but the Rams stalled late; Kyren Williams fumbled near the goal line, and Puka Nacua kept the air busy with 10 receptions for 76 yards and a TD. The 49ers’ defense held on a crucial OT stop, setting up a Week 6 clash with Tampa Bay.