Joe Burrow is set up as a premier game-script winner for 2025, with Cincinnati’s defense continuing to pressure the opposition and Burrow airing it out to a high-volume target group. Expect Ja’Marr Chase and Tee Higgins to reap rapid-volume days when the defense struggles, while early-backfield pressure from the pass rush could keep Burrow under constant prime-for-pass attempts. For fantasy, Burrow-specific stacks could be ideal as Cincinnati’s offense remains a constant high-floor, high-ceiling engine.

Kenneth Walker III carries obvious risk but big upside if he stays healthy and Seattle’s offense keeps the run-first pace. Seattle’s new scheme favors zone runs and a workload spike if the line improves, making Walker a candidate for both explosive games and plus-matchup weeks. For Dynasty or keeper formats, his dynamic burst can pay dividends when health cooperates.

Calvin Ridley should see a notable volume uptick with Cam Ward in Tennessee, and Ridley’s big-play profile fits a Titans offense that will lean on passing to compensate. The improved accuracy and arm strength Ward brings could yield a steadier catch rate and more consistent targets, elevating Ridley’s weekly upside in 2025 drafts.

Bo Nix faces a potentially different game-script reality in Denver. While his rookie-year efficiency was strong, a better running game and a defense that’s improved could trim his volume slightly. The quarterback’s rushing floor remains, but fantasy managers should temper expectations for the same high-volume pass attempts seen in 2024. Bo’s path to value lies in efficiency and timely deep-ball connects rather than sheer volume.

Lastly, rookie pages like Tetairoa McMillan and Brian Thomas Jr. show sneaky upside in favorable game scripts. If defenses tilt to stop a run-heavy Seahawks or a pass-heavy Bengals, these youngsters could steal late-season touches and deliver strong waiver-wire returns in dynasty or best-ball formats.