Panthers’ Week 2 outlook tightens as injuries hit the trenches. Wharton’s hamstring will sideline him 2-4 weeks, testing interior depth while Nijman’s Week 1 effort underscored protection issues. Renfrow’s rib injury adds another cut to the receiving corps, with Jones II limited and Crumedy/Jaden Crumedy stepping into larger roles. Cam Jackson could push for more snaps behind Wharton, reshaping the Panthers’ front seven against Arizona.

Fantasy angles shift quickly: Renfrow’s status could boost other receivers in a game Carolina leans on quick throws and run game tempo. With the rookie interior guys stepping up, IDP edges may see increased opportunity, and Young’s sophomore season starts under new pressure, raising the stakes for Week 2 projections and DFS lineups.