Week 2 MNF pivots on inactives as Houston and Tampa Bay shuffle roles for Monday night. Dameon Pierce is a healthy scratch for Houston, with British Brooks stepping in as the primary back as Jake Andrews sits with an ankle injury and Jarrett Patterson takes over at center. Christian Kirk and Braxton Berrios are sidelined again, thinning Houston’s WR corps. Graham Mertz remains the Texans’ third QB while Tommy Togiai is inactive. Tampa Bay rests Chris Godwin and Tristan Wirfs; Luke Goedeke will start, with Devin Culp, Tez Johnson, Josh Williams and Rashad Wisdom out.

Inactives force a reshaped game plan on both sides. For fantasy managers, Pierce’s absence tightens Houston’s backfield usage around Brooks, while the Texans lean on Patterson’s center duties and the wider depth chart. For Tampa Bay, the conqueror of the line remains unsettled until Goedeke clears, pressuring the Buccaneers’ pass and run schemes without their top weapons.

Ryans says the 53-man squad is really good, with roster moves still possible as the season nears. The Texans will lean on a heavy defensive-line rotation (10 DL) to keep players fresh, and Togiai earned his spot through relentless work and consistency.

Mixon’s injury status is day by day, while Stroud and Anderson are highlighted as leaders. Graham Mertz showed upside as a third quarterback. Strong OL depth and veteran presence underpin a roster built to contend against the Rams in Week 1, emphasizing leadership, depth, and protection of players’ privacy around injuries.

Houston's roster cutdown discourse centers on ongoing fluidity and workload splits ahead of a Week 1 test against the Rams. Joe Mixon’s NFI status creates immediate backfield questions, while British Brooks and Tommy Togiai earn worker-bee credibility and could shape early-down roles. Graham Mertz remains a key third quarterback, CJ Gardner-Johnson's status looms over the secondary, and Aireontae Ersery plus Kamari Lassiter offer position-flexible depth that could spark waiver-period moves.

Fantasy players should monitor practice reps and waivers as Houston leverages a marathon-not-sprint approach to roster construction. Expect several 53-to-53+ adjustments, with practice-squad and in-season calls influencing weekly lineups, especially at RB and on defense where versatility matters most.