Tennessee arrives Week 6 in Las Vegas with a thinning depth chart: Slye, Arden Key, Blake Hance, Marcus Harris and Bryce Oliver ruled out; JC Latham and Van Jefferson listed as questionable. Las Vegas counters with Brock Bowers out and AJ Cole nursing a questionable ankle. Fantasy managers should watch Latham and Jefferson’s odds to play, and anticipate extended opportunities for Titans depth pieces or Raiders options if injuries linger.

Without Bowers, Raiders’ TE usage could shift, while Titans’ blockers and receivers may lean on swing players or practice-squad depth. This matchup could shape Week 6 decision-making at both offense and special-teams positions, especially around field-goal probability and WR streaming targets.