Colts-Raiders Week 5 injury report reshapes fantasy usage. Alec Pierce is out with a concussion. If AD Mitchell’s playing time isn’t guaranteed, Ashton Dulin could step in, creating volatility at the Colts’ X/slot roles. Kenny Moore is out; Mekhi Blackmon likely starts outside, with Tyquan Lewis questionable and rookie JT Tuimoloau stepping in if he can’t go. Daniel Scott is out, thinning the Colts’ secondary.

Raiders’ tight ends Brock Bowers (knee) and Michael Mayer (concussion) sit at the edge of game status, while Eric Stokes (knee) is also questionable. If Bowers sits, Mayer may command more targets; if active, Vegas leans on a short-to-intermediate attack. Inactives arrive 90 minutes before kickoff, so late-week updates will drive final fantasy decisions.

Raiders injury updates loom large as Mayer’s status remains unclear and Kolton Miller nurses a high ankle sprain, pushing Stone Forsythe into left tackle duties. Ashton Jeanty is earning more touches while the line rotates, and Eric Stokes returns from a knee sprain, shaping depth and rotations. Across the league, Daniel Jones thrives in Steichen’s system with Tyler Warren emerging as a premier target and a talented tailback driving NYG’s attack.

Fantasy takeaway: Mayer’s timeline and Forsythe’s workload will dictate LV’s ceiling; monitor Stokes’ health and Jeanty’s usage. Jones and Warren signal sustained NYG target volume, while Raiders depth and coaching tweaks create upside in deeper formats. Health, development, and scheme tweaks remain the keys to value this season.

Colts vs. Raiders in Lucas Oil Stadium shapes up as a fantasy-friendly test: Indy sits 3-1 atop the AFC South while Vegas looks to rebound from a tight loss. Ashton Jeanty’s Week 4 breakout boosts Raiders’ backfield optimism and Brock Bowers enters Indy’s targets in the matchup’s narrative. Injury notes for Mayer, Pierce and others could tilt snap shares and opportunity as the game unfolds.

Odds tilt Indy, but only by a hair, with a -6.5 spread and a 47.5 total. Rogers-like turnover pressure on Geno Smith and Jones’ ball security will be pivotal; Jeanty and Indy’s improved run-pass mix should shape DFS value and weekly bets.