Indy dominated the Raiders 40-6 behind a balanced attack and a relentless defense. Daniel Jones looked like the franchise quarterback Indy hoped for, delivering 212 yards and two touchdowns with composure under pressure. Jonathan Taylor punched in three scores as Indy carved out a red-zone clinic (6-for-6). Defensively, four Colts sack a list of stalwarts while Laiatu Latu and Mehki Blackmon delivered timely takeaways. Special teams shone with a blocked punt by Segun Olubi as Indy proved it can win in all three phases.

Offensive cohesion and red-zone efficiency were the storylines, but the Colts’ improved protection allowed Jones to exploit Raiders’ coverage and keep the momentum. With several pass-catchers contributing, Indy’s weapons pool looks more versatile than earlier in the season, giving fantasy managers a clearer path to steady weekly points and upside in a favorable schedule ahead.

Week 5 fantasy outlooks center on high-volume targets for Emeka Egbuka in Tampa Bay as Mike Evans heals, making him a clear WR1 candidate in a pass-happy game plan. Tetairoa McMillan is cleared for Week 5 but faces a sputtering Panthers attack, projecting as a high-end WR3 with steady target equity. Denver’s backfield remains a fluid mix among Bhayshul Tuten, Ashton Jeanty, Omarion Hampton and RJ Harvey, with Harvey showing flex potential in a developing role. Jaxson Dart brings a tangible floor for the Giants with rushing upside, while Elic Ayomanor offers Titans flex appeal. Isaac TeSlaa and Travis Hunter add depth chart intrigue. Use the Who Should I Start tool to compare up to four players and lock in Week 5 decisions.

Rookies in 2025 fantasy football are delivering mixed early returns through Week 5. Cam Ward’s Titans have yet to click offensively, while Jaxson Dart for the Giants shows reliable rushing upside and streamer potential. The Browns have installed Dillon Gabriel, with a few other rookie passers in the mix behind him. At receiver, Emeka Egbuka and Tetairoa McMillan lead the rookie pass-catchers, though usage remains volatile across teams. In the backfield, Ashton Jeanty, Omarion Hampton and Quinshon Judkins stand out as high-ceiling options, with Henderson and Skattebo offering week-to-week flex appeal. Tyler Warren is the clear TE standout among rookies, while the rest of the class shows wide-ranging paths to fantasy relevance.

Expect continued volatility as coaches balance rookie ceilings with real-game constraints. The quarter-season picture favors those who survive early inefficiencies and land on offenses that lean into rookie strengths—mobile QBs, high-volume pass-catchers and workhorse backs. Dynasty managers should note long-term upside from the WRs and TEs, while redraft managers screen for week-to-week pipelines in the tougher matchups.

Overall, the rookie class is far from uniform, but the top names offer compelling upside in the right roles, with a few paths to weekly fantasy relevance emerging as the season unfolds.