Saints defense eyes a marquee Week 2 upset as a hobbled 49ers squad visits New Orleans. With Purdy, Kittle, and Aiyuk sidelined or limited, Spencer Rattler and a rebuilt Saints attack must lean on a stout defense and a smarter game plan to steal a win.

Bold projections color the page: a pass rush that adds five sacks, Rashid Shaheed erupting for big yards, and Cameron Jordan delivering multiple sacks. In a low-scoring, defense-driven game, fantasy managers should chase Saints playmakers while tempering expectations for the visiting offense.