Week 1 injury notes shape Cardinals at Saints fantasy decisions. Kyler Murray will play despite an illness; Arizona’s line could be tested with Will Hernandez out and Owen Pappoe questionable. New Orleans lists Chase Young out and Trevor Penning questionable toe, with Jordan Howden (oblique) and Khristian Boyd (hand) limited, Alontae Taylor groin. Spencer Rattler starts for the Saints, under rookie coach Kellen Moore, adding intrigue for DFS and in-season bets.

Key shifts: Murray’s health remains a non-issue for fantasy ceilings; Saints’ edge absence could alter quick-pass tendencies and target shares. Injuries to interior OL and secondary players on both sides create upside scenarios for a handful of secondary types in Week 1.