The New Orleans Saints have a rich history of strong defensive players, with significant contributions to the team's tackles for loss (TFL) in franchise history. Leading the pack is Cameron Jordan, who has established himself as a cornerstone of the Saints' defense since joining the team in 2011. With a remarkable 160 tackles for loss, Jordan's relentless pursuit of ball carriers has made him a formidable force on the field.

Following Jordan is Will Smith, who dominated the field from 2004 to 2012, amassing 85 TFLs. Not far behind are current players like Demario Davis and Carl Granderson, showcasing the Saints' ability to blend veteran experience with emerging talent. The list also includes standout names from past generations, highlighting the team’s longstanding commitment to defensive excellence.