Arizona faces Philadelphia in Phoenix as Diamondbacks shake up their late-season plan. A MLB debut call-up, a 10-man bullpen, and a four-man rotation for the final nine games shape the arms map while Abner gets his first big-league outing. The D-backs lean on Ketel Marte and Corbin Carroll to spark the lineup, with Adrian Del Castillo and Alek Thomas providing depth as the prospect narrative grows. Expect bullpen-heavy late outs and careful usage with an off day shaping weekend rest dynamics.

Lineup notes tilt toward power and speed from the Phillies with Bader in CF, Harper at 1B, and Schwarber as DH, backed by Realmuto and Stott. The D-backs counter with a mix of power and contact from Bohm and Del Castillo, plus Tawa and Wilson pieces in the middle. Stranger Things Night adds a local buzz, but the on-field focus remains on bullpen strategy, rotation timing, and the evolving late-season grind for both clubs.

Week 22 in fantasy baseball centers on hitters riding momentum and playing time upside. Michael Harris II has turned his season around after a swing adjustment, riding an 11-game streak with strong counting stats and elite underlying metrics. Jake McCarthy has blasted to the top of the last-week batting averages, reminding managers of his spark Plug capability if he earns regular at-bats in Arizona. Miguel Andujar has made a standout impression with Cincinnati, delivering big RBI numbers and a high wRC+ while fitting neatly into middle-of-the-order spots.

Jose Caballero leads the league in steals while his playing time remains the gating factor; a hot minute or two of extra ABs could unleash even more baseline value. Myles Straw and Mike Yastrzemski have shown wheels and power in recent days, particularly when hitting leadoff or top of the lineup, making them solid cheap DFS or roto targets as the season winds down. August wRC+ leaders Brice Turang, Jakob Marsee, and Shea Langeliers headline the sprint for late-season breakouts, with Langeliers anchoring Oakland’s catching corps and Turang providing growing base-path value as the season nears its close.

Lineup optimization this week leans on strong batting averages, RBI potential, and stolen base upside from the new wave of breakouts. For fantasy managers, the takeaway is to roster Harris II, McCarthy, Andujar, Caballero, Yastrzemski, and Straw where possible, while eyeing Turang, Marsee, and Langeliers as longer-term upside bets who could fuel “Week 22” results and beyond.