Chargers waiver-wire churn and a 16-man practice squad loom large as San Diego readies for Week 1. Harbaugh oversees depth moves, stash targets, and cross-league adds while shielding key youth. Trey Lance lands on the roster behind Herbert, offering a mobile backup and gadget-potential, while Taylor Heinicke exits. Asante Samuel Jr. returns on a timeline after offseason surgery, adding a fortified corner depth chart and shaping opponents’ fantasy plans.