Mac Jones is set to start for San Francisco after a knee scare, with Adrian Martinez not elevated. Eli Apple was added from the practice squad for Sundays game against Jacksonville, signaling confidence in the rest of the depth chart. Ricky Pearsall and Jauan Jennings are questionable but likely to play, keeping Bourne, Robinson, Valdes-Scantling and Skyy Moore as viable targets if one sits. Colby is questionable; Moss or Zakelj could step in. Brandon Aiyuk’s absence remains the defining storyline for the offense.

If Pearsall and Jennings sit, the 49ers would lean on a shallow WR corps; if one plays, expect a broader distribution with the expected nod to Bourne and the Chiefs pairing of Robinson, Valdes-Scantling and Moore. The 49ers will list inactives 90 minutes before kickoff at Levi’s Stadium.

Apple elevated from the 49ers’ practice squad ahead of Week 4 versus Jacksonville, giving San Francisco veteran depth at cornerback behind Renardo Green, who is dealing with a neck issue and listed questionable. Green played 86% of snaps last week but was limited in practice. The WR group isn’t being boosted with an elevation, as Demarcus Robinson and Jauan Jennings are the primary targets with Pearsall likely to play if limited.

Keith the depth chart: Deommodore Lenoir, Darrell Luter Jr., Chase Lucas and Upton Stout provide cover in the secondary, while Pearsall, Jennings, Robinson, Skyy Moore and Marques Valdez-Scantling headline the Week 4 receiving corps. Levi’s Stadium hosts the 1:05 p.m. kickoff against the Jaguars.

San Francisco’s 2025 practice squad spotlights camp standouts and a pair of likely signings who could swing fantasy odds this year. Adrian Martinez, Sincere McCormick, Robbie Chosen, Drake Nugent and Eli Apple anchor a depth chart built to contribute behind the active roster, with Nugent and Nick Zakelj adding interior line flexibility and Chosen offering veteran pass-catching upside. This mix signals SF’s plan to weather injuries and suspensions, a smart angle for fantasy managers tracking late-season surges.

For fantasy and bets, Martinez and McCormick stand out as potential late-season inputs, while Nugent and Apple provide stabilizing floor for SF’s rotation. Bergen’s presence adds a special-teams lift, and Nugent’s preseason showing hints at a longer arc for interior depth. Watch how SF leverages this group when Week 1 rolls around and injuries test the depth chart.

Eli Apple reflects on his tumultuous journey with the New York Giants, shedding light on the struggles he faced as a young cornerback thrust into the NFL spotlight. Drafted 10th overall in 2016, Apple's early career was marred by personal and professional challenges, leading to a midseason trade to New Orleans in 2018. As he navigated media scrutiny and internal conflicts, Apple learned vital lessons about growth and resilience. Now a free agent at 29, he acknowledges the chaos of his Giants tenure as a necessary step in his evolution, emphasizing gratitude for the opportunity despite its difficulties.

The Los Angeles Chargers have decided not to promote veteran running back Ezekiel Elliott from their practice squad ahead of their AFC wild-card match against the Houston Texans. Elliott, who was signed on Tuesday, only participated in three practices after being released by the Dallas Cowboys on December 31. The Cowboys' intention was to allow him to join a playoff team in need of seasoned running back talent.

In a series of roster adjustments made on Friday, the Chargers activated cornerback Eli Apple and wide receiver Simi Fehoko from injured reserve. Defensive back Ja’Sir Taylor was placed on IR, while safety Eddie Jackson and running back Jaret Patterson were elevated from the practice squad. Apple has played in four games this season for the Chargers but has been sidelined for the last six due to a hamstring injury. Fehoko, who suffered an elbow injury on November 3 against the Cleveland Browns, has missed the last nine games of the regular season.