Harbaugh outlined a flexible Chargers secondary, with Derwin James sliding inside, Elijah Molden providing versatility, and Tony Jefferson anchored in the rotation. Jefferson’s value remains high and his presence is felt in the locker room and on the field, even if Molden returns healthy.

Alohi Gilman is in the mix as the unit swarms the Giants, while the coaching staff searches for the right balance of speed and coverage. The plan hinges on depth, rotation, and Harbaugh’s culture, highlighting how depth pieces could shape the defense in Week 4 and beyond.

Chargers head east to face the winless Giants with a favorable setup for fantasy managers. Through three weeks, LA sits among the league’s top units in total and passing yards, while New York’s defense has been torched, especially through the air. Omarion Hampton appears primed for a 100-yard rush day as the running game benefits from a vulnerable Giants front, and WRs Quentin Johnston and Keenan Allen should continue to pace the receiving corps.

Defensively, the Chargers have been stingy, limiting both yards and points, setting the stage for a disciplined game script. If Justin Herbert can exploit the Giants’ soft rush and secondary, Los Angeles should push toward 4-0. Fantasy players might target Herbert, Hampton, and the Chargers’ pass-catching trio, while the Giants’ skill players carry a high-risk, high-reward profile in this matchup.

Chargers' defense steals the show in a 20-9 win over the Raiders as Herbert labors yet LA improves to 2-0. Through two weeks, the unit sits among the league’s stingiest, having allowed only 30 points and not a single first-half TD. The defense harassed Geno Smith all night, combining three interceptions, three sacks, and relentless pressure that kept Las Vegas from threatening late.

Daiyan Henley anchors with 10 tackles (2 for loss), an interception, two pass defenses and an 11-yard sack; Quentin Johnston breaks through with a 60-yard score after Week 1 success; Tony Jefferson shines after a late call-up with a key end-zone breakup and a pick near the goal line. Jesse Minter’s group clamps down on the run and soldiers through a long, grueling drive to seal it.

Cardinals No. 22 history gets a long look as the 2025 season opener against the Saints nears, with Michael Carter wearing 22 in Arizona and spotlighting a lineage that stretches back to Eddie Anderson in the 1920s. The list runs through Emmitt Smith in 2003-2004, Tony Jefferson in 2013-2016, and Roger Wehrli, the Hall of Famer regarded as the best to ever wear 22 for the Cardinals. The countdown frames a roster-tenure narrative across decades, tying past greats to the present backfield battle.

Wehrli stands as the standout, but the piece emphasizes the broad tapestry of players who have slung, caught, or carried No. 22 in Cardinals lore, culminating in a reflection that the number has carried different meanings across eras—from stalwart defenders to breakout backs. The feature closes by plugging Cards Wire’s Rise Up, See Red podcast for more Cardinals and NFL coverage.