Chargers week-one exploits a dangerous wide-receiver trio led by Keenan Allen and Quentin Johnston, with depth pieces sparking the offense and Herbert distributing efficiently. A Denzel Perryman injury forces new LB rotations, while Khalil Mack and the pass rush aim to elevate the defense. If the running game unlocks even modest gains, this offense could be a top-10 unit again in 2025.

The fantasy angle centers on Herbert spreading targets, Johnston's red-zone growth, and Allen’s steady floor, all while the defense relies on Mack and a reshuffled linebacker group. Health and run-game progress will largely determine sustained fantasy upside across the core players.