Two primetime West Coast rivals collide in Las Vegas as the Chargers visit the Raiders in the second MNF game. Both squads opened with Week 1 wins, and the victor will sit alone atop the AFC West. ESPN has the Chargers favored by 3 with an over/under of 46.5, and kickoff is set for 7:00 p.m. local time. The matchup carries coaching chatter between Harbaugh and Carroll, adding narrative weight to a game that should shape early-season fantasy narratives.

Fantasy managers should monitor how the game unfolds for pass-catchers and backfield usage in a likely close, high-leverage affair. Game flow could tilt opportunities for top playmakers depending on pace, tempo, and how each team leans on passing or grinding the clock in a pivotal Week 2 contest.

Chargers 34, Raiders 20. Geno Smith’s Vegas home debut starts rough with an early interception, but Daniel Carlson’s 54-yard field goal answers. Ashton Jeanty’s 13-yard burst and Dont’e Thornton’s 20-yard catch provide a spark, while Khalil Mack sacks Smith and Eric Stokes disrupts early. Next up, Washington on Sunday at 10 a.m. PT as Vegas seeks a rebound.

Rachaad White caps a dramatic 20-19 comeback for Tampa Bay in Houston with a 2-yard TD run as six seconds remain. Baker Mayfield lashed two TDs on 25-of-38 for 215 yards, fueling a 2-0 start for the Buccaneers. Houston pressed late behind a punt return and a blocked punt but couldn’t seal it, leaving Nick Chubb's TD run as a late spark. Joe Burrow faces toe surgery and months out; Minnesota’s J.J. McCarthy injures an ankle; Colts sit 2-0. A crowded slate reshapes fantasy value as Chargers and Raiders loom.

Two Monday Night Football games cap Week 2: Texans at Buccaneers at 7 p.m. ET and Chargers at Raiders at 10 p.m. ET, with Monday MLB Rays at Blue Jays in play. DraftKings promo codes reward new users with $200 in bonus bets and $200 off NFL Sunday Ticket, fueling daily fantasy lineups and bets across NFL and MLB.

The SportsLine model backs a Tampa Bay upset in Houston, plus a Chargers-Raiders clash driven by ground-game pace, projecting the Under. A three-pick Monday parlay via DraftKings pays +712. The slate leans on Baker Mayfield’s steadiness, rookie backfields, and Rays’ underdog heat, all shaping smart DFS and betting decisions for Week 2.