Philadelphia must reestablish trust between Jalen Hurts and Nick Sirianni as a run game and pass protection struggle. The Giants upset exposes coaching and quarterback questions as Daboll navigates a fragile offense. Ravens and Chargers battle a laundry list of injuries, forcing ad hoc lineups and smarter game plans. Fantasy angles center on Hurts rushing floor, Brown/Smith targets, and how post buy weeks shift backfield roles across Baltimore, LA, and beyond.

Across the league, CJ Gardner Johnson adds bite for Baltimore while Slater and Mack shape pass pro and run game for the Chargers. The ripple effect hits Dak’s division rivals and the rest of the NFC/ AFC landscape, where injuries and coaching decisions will decide who rebounds in the weeks ahead and which backfields offer the clearest paths to fantasy points.