Los Angeles Chargers enter 2025 with Jim Harbaugh’s system in hand and Justin Herbert at the controls, a combination that kept the offense efficient and downfield-ready last season. Herbert thrived, rising to elite passing grades and attacking vertically, paving the way for a high-octane attack even as receiving depth remains a concern. The defense remains the story, anchored by Derwin James Jr. and Khalil Mack, producing a top-tier secondary that again stifles explosives and bolsters fantasy appeal across the roster.

Depth at wide receiver behind Ladd McConkey is uncertain after Joshua Palmer’s departure and limited upside from Quentin Johnston and Keenan Allen, which could compress targets. The Chargers’ rookie add Omarion Hampton is framed as a potential lead back on a run-first approach, although Najee Harris presence elsewhere signals that a clear-cut top-10 rookie back is unlikely early. A notable fantasy edge comes from Herbert’s big-play ability; the best bet on the board remains Herbert over 21.5 passing touchdowns, a line he eclipsed previously as the offense evolved under Harbaugh.

Bottom-line takeaway: Rashawn Slater’s injury risk is real, but Harbaugh has yet to post a losing season in this NFL run. Even with depth questions, the Chargers project as postseason contenders thanks to a pass-defense backbone that should carry the defense in tight games, while Herbert’s downfield rhythm keeps fantasy managers hopeful for breakout weeks.