São Paulo hosts Week 1 Friday Night Football as Kansas City visits Los Angeles. KC is a -3 favorite on a neutral field, with Mahomes aiming to reconnect downfield while Slater sits for the Chargers and Alt slides in at left tackle. Isiah Pacheco is expected to shoulder major rushing/receiving work, especially with Rashee Rice suspended. The betting card leans to Pacheco over 60.5 total yards, Omarion Hampton under 65.5, and Tre Harris under 31.5 receiving yards.