Patriots-Bills Week 5 inactives reshape fantasy expectations. Carlton Davis and Milton Williams are active, anchoring New England’s secondary and interior line as Jahlani Tavai returns. K'Lavon Chaisson is out, likely boosting Keion White’s rush opportunities against Josh Allen. Efton Chism III remains inactive, stalling rookie WR upside.

Bills list Elijah Moore, Ed Oliver, Dorian Williams, Jordan Hancock, Brandon Codrington, Chase Lundt, and T. J. Sanders as inactive, signaling clearer target trees and fewer interior disruptors for Buffalo. Snap and scheme shifts could tilt value on both sides, especially for edge rushers and defensive units in DFS.

The New England Patriots list four players as questionable for Week 5 against the Bills: Milton Williams, Carlton Davis, K’Lavon Chaisson, and Jahlani Tavai. If Williams cannot go, Cory Durden would likely start inside, a move that could slightly curb the interior pressure drop. New England’s front has surged this season, now pressuring at a league-average clip (35.5%), with Christian Barmore, Williams, and a reworked scheme spearheading the effort. Tavai’s calf injury casts a shadow over the back‑seven’s depth and the activation window looms large, while Davis and Gonzalez anchor a renewed perimeter curb. Buffalo looms large, with Keon Coleman and Dalton Kincaid as key mismatch points for the Pats’ coverage.

The Week 5 status compounds a game that could hinge on the Pats’ ability to sustain pressure and disrupt Buffalo’s timing. If Williams plays, the Patriots’ front could tilt toward more disruptiveness and quicker QB harass. Davis’ return adds matchup flexibility against Bills receivers, while Chaisson’s availability directly affects edge rush tempo. With Tavai’s activation window uncertain, New England will need to balance upside with roster risk as they chase a pivotal division win.

Detroit signs Tre Flowers to the practice squad, adding veteran depth as D.J. Reed and Terrion Arnold miss time. Amik Robertson shifts outside; Lions may deploy Rock Ya-Sin or Khalil Dorsey at the other outside slot if Arnold cannot play.

With Maddox able to handle the slot in a pinch, Detroit reshapes its secondary ahead of a Week 5 clash with Cincinnati. Flowers’ experience and four career interceptions give the defense a-needed floor behind a young core that includes Carlton Davis III, Robertson, and Maddox, while the depth chart remains fluid as injuries linger.