New England Patriots Week 5 injury report ahead of the primetime clash with Buffalo shows key questions on the edge and in the secondary. K'Lavon Chaisson knee and Jaylinn Hawkins hamstring leave both outside linebackers and safeties in flux, while Jahlani Tavai returns as a limited participant after IR. Several Patriots linemen and linebackers logged limited work, and Will Campbell came back to full participation after a shoulder issue. Bills' side lists multiple non-participants or limited players as well, setting up a high-stakes fantasy showcase.

Buffalo’s Dorian Williams knee kept him out, Matt Milano (pectoral) and Ed Oliver (ankle) were limited, Spencer Brown (calf) and Jackson Hawes (ankle) followed with limited practice. No Bills players were listed as fully participating. The Week 5 picture hinges on edge depth, LB rotation, and the health of interior lines, with fantasy managers eyeing snap shares and potential upside if injuries linger.

New England padded Week 4 depth by adding Royce Newman and Gee Scott Jr. to the practice squad, signaling a practical plan for protection and receiving help against Carolina. Newman, a veteran interior lineman with Packers and Buccaneers stops, can back up or start at guard as needed. Scott, Ohio State alum who moved from WR to TE, brings blocking and receiving versatility that could surface in two-TE looks and red-zone packages.

With Jared Wilson banged up and Hunter Henry’s knee health monitored, the Patriots are layering contingency options for Week 4. Scott’s arrival could translate into immediate two-TE alignments, while Newman provides insurance on the interior line. The Panthers’ front will test interior depth, making this roster shuffle a fantasy-adjacent storyline—potential early impact with injuries, and longer-term depth that could shape the offense’s protection and pass-game options.

Beyond New England, the week’s activity includes Mark Robinson joining the Jets at linebacker and Thayer Munford Jr. landing with the Browns at tackle, underscoring a league-wide emphasis on practice-squad depth as teams prep for Sunday action. The matchup in Foxborough presents a genuine test for interior blocking and tight-end versatility, with fantasy angles centered on run efficiency and short-to-mid-range targets.

Patriots dodge injury bullets in Week 3 after a 21-14 setback to Pittsburgh. Drake Maye absorbed edge pressure but logged every snap, Hunter Henry left briefly with a leg issue and returned, and Jared Wilson shook off a stinger to stay in the game. TreVeyon Henderson chipped in but wasn’t sidelined by the clash. Adrenaline may mask symptoms, yet Week 4 looks plausible pending practice reports and concussion checks.