Patriots-Bills Week 5 inactives reshape fantasy expectations. Carlton Davis and Milton Williams are active, anchoring New England’s secondary and interior line as Jahlani Tavai returns. K'Lavon Chaisson is out, likely boosting Keion White’s rush opportunities against Josh Allen. Efton Chism III remains inactive, stalling rookie WR upside.

Bills list Elijah Moore, Ed Oliver, Dorian Williams, Jordan Hancock, Brandon Codrington, Chase Lundt, and T. J. Sanders as inactive, signaling clearer target trees and fewer interior disruptors for Buffalo. Snap and scheme shifts could tilt value on both sides, especially for edge rushers and defensive units in DFS.

New England patched the roster ahead of the Bills game: K'Lavon Chaisson is out, Jahlani Tavai is back from IR, and Milton Williams travels with the team though limited by an ankle issue. Chaisson’s absence flags Keion White for more edge reps, potentially setting up a breakout against Josh Allen. Williams’ status adds a potential interior disruptor if he can go, while Tavai’s return stabilizes New England’s linebacker group in a must-win matchup.

The Patriots lean on Drake Maye’s growing command and a space-reading offense that thrives with Hunter Henry over the middle and Rhamondre Stevenson out of the backfield. Maye’s improvement in processing and pocket feel is tempered by occasional overextension, but McDaniels draws downfield opportunities and keeps a strong run game in reserve. New England’s front is creating pressure, while the Panthers’ offense could struggle against a full-strength defense. Special-teams edge and field-position battles shape the outcome.

Christian Gonzalez’ health is a key variable, but the cornerback pool remains strong. Milton Williams anchors interior pressure, with Landry and Chaisson providing edge punch. The Panthers’ star power is balanced by Ryan Fitzgerald’s kicking and situational tricks, making this a game where football IQ and discipline could tilt the result in New England’s favor.

Keion White is back from illness and eyeing a fuller edge role with the Patriots, but Chaisson and Landry still pace ahead. A two-game lull with 42 snaps and zero QB disruptions hasn’t derailed the plan; the staff expects him to reclaim starting pace once he’s fully ramped.

If White translates his burst timing and inside rush potential into consistent pressure against zone reads, the Patriots’ edge rotation could swing in his favor in the coming weeks, providing a tempting sleeper in dynasty and Fantasy IDP formats.