Patriots-Bills Week 5 inactives reshape fantasy expectations. Carlton Davis and Milton Williams are active, anchoring New England’s secondary and interior line as Jahlani Tavai returns. K'Lavon Chaisson is out, likely boosting Keion White’s rush opportunities against Josh Allen. Efton Chism III remains inactive, stalling rookie WR upside.

Bills list Elijah Moore, Ed Oliver, Dorian Williams, Jordan Hancock, Brandon Codrington, Chase Lundt, and T. J. Sanders as inactive, signaling clearer target trees and fewer interior disruptors for Buffalo. Snap and scheme shifts could tilt value on both sides, especially for edge rushers and defensive units in DFS.

Milton Williams is expected to play for New England against Buffalo after an ankle issue, giving the Patriots a crucial interior disruptor for a primetime AFC East showdown. Williams’ availability should help slow Josh Allen and shrink Buffalo’s run lanes.

If Williams is limited, the Bills may lean on Allen’s improvisation and quick passing, boosting their fantasy upside; Williams’ status also shifts Patriots’ IDP value and overall defensive ceiling. Fantasy managers should track final injury designations and snap counts as kickoff approaches.

New England patched the roster ahead of the Bills game: K'Lavon Chaisson is out, Jahlani Tavai is back from IR, and Milton Williams travels with the team though limited by an ankle issue. Chaisson’s absence flags Keion White for more edge reps, potentially setting up a breakout against Josh Allen. Williams’ status adds a potential interior disruptor if he can go, while Tavai’s return stabilizes New England’s linebacker group in a must-win matchup.

The New England Patriots list four players as questionable for Week 5 against the Bills: Milton Williams, Carlton Davis, K’Lavon Chaisson, and Jahlani Tavai. If Williams cannot go, Cory Durden would likely start inside, a move that could slightly curb the interior pressure drop. New England’s front has surged this season, now pressuring at a league-average clip (35.5%), with Christian Barmore, Williams, and a reworked scheme spearheading the effort. Tavai’s calf injury casts a shadow over the back‑seven’s depth and the activation window looms large, while Davis and Gonzalez anchor a renewed perimeter curb. Buffalo looms large, with Keon Coleman and Dalton Kincaid as key mismatch points for the Pats’ coverage.

The Week 5 status compounds a game that could hinge on the Pats’ ability to sustain pressure and disrupt Buffalo’s timing. If Williams plays, the Patriots’ front could tilt toward more disruptiveness and quicker QB harass. Davis’ return adds matchup flexibility against Bills receivers, while Chaisson’s availability directly affects edge rush tempo. With Tavai’s activation window uncertain, New England will need to balance upside with roster risk as they chase a pivotal division win.