Kyler Murray starts Week 1 vs New Orleans after a Sunday illness tag, a reminder that even healthy-looking game days can hinge on on-morning updates. The Cardinals will lean on Murray’s rushing ceiling if he’s close to full health, but the illness could trim his explosive upside just enough to matter in fantasy lineups.

Jacoby Brissett is the new emergency for Arizona, with a long track record across multiple clubs, ready to step in at a moment’s notice. The Saints present a tough matchup, so if Murray is limited, Brissett’s cue to fantasy managers is to monitor play-caller tweaks and potential target-shares for Cardinal pass-cats in a pinch.

The Cardinals signed Kedon Slovis to their practice squad, a homecoming reverberating through a quarterback room led by Kyler Murray and Jacoby Brissett. Slovis, a former Arizona high school standout, will serve as the emergency third option behind the duo, with the playoff chase hinging on Murray’s health. His path to real action remains slim absent an injury or unforeseen roster move.

Slovis’ NFL journey includes a 2024 rookie stint with the Colts and practice-squad time with the Texans before this Cardinals move. Fantasy managers should note: this is depth to preserve stability, not a viable fantasy streamer unless circumstances force a rare on-field opportunity.

Kidon Slovis signs with the Arizona Cardinals on their practice squad, a hometown Scottsdale product who starred at Desert Mountain High. After a 2025 preseason with the Houston Texans, he enters 2025 as Kyler Murray’s third-string behind Murray and Jacoby Brissett, giving Arizona a skilled emergency option and a path back to the active roster if needed.

This move adds QB depth for fantasy considerations, highlighting Slovis’ developmental arc and the Cardinals’ willingness to stash a promising, local signal-caller as they navigate a competitive QB room in 2025.

Arizona’s preseason finale vs. Las Vegas spotlights backups and roster scrambles as starters sit. Clayton Tune leads the QB audition, with Jacoby Brissett on the depth chart behind Kyler Murray, not suiting up. Xavier Weaver and Josh Fryar push for final spots, while P.J. Mustipher and Kitan Crawford fight for meaningful depth roles. Joey Blount and Walter Nolen add special-teams and DL intrigue. Outcomes matter less than tape and roster signals for fantasy depth pieces.

Luck's 2019 retirement kicked off a Colts QB carousel, with Brissett starting 15 in 2019, Rivers in 2020, Wentz in 2021, Ryan in 2022, then Ehlinger, Foles, and Minshew through 2022-2023. Richardson became the 2023-24 focal point with 15 starts, followed by Flacco in 2024. Daniel Jones emerges for 2025 with starts listed as N/A. The era highlights volatility at the position and the rising appeal of Richardson’s rushing upside for fantasy managers.

Fantasy players should weigh upside vs. reliability: Richardson offers top-end ceiling; Jones brings unknowns in 2025; the Colts still lack a clear, consistent long-term QB. Draft strategies should consider rushing equity, supporting cast, and the rapid turnover that defined Indianapolis’ post-Luck era.